In cases of neonatal sepsis, which of the following organisms is commonly associated with Group B streptococcus as a pathogen?

Group B Streptococcus (GBS) is a major pathogen associated with neonatal sepsis, particularly in the early onset of the disease. Among the organisms commonly found in conjunction with GBS, E. coli is frequently identified as a co-pathogen. In newborns, especially preterm infants, E. coli is often implicated due to its presence in the maternal or neonatal gastrointestinal tract and its ability to cause infections in a vulnerable population.

The relationship between GBS and E. coli is significant because infections with these bacteria can arise from similar risk factors, including maternal colonization and perinatal factors. When a neonate presents with sepsis, both organisms may be cultured from the blood or other sites, reinforcing the idea that they can coexist as pathogens in these cases.

While Chlamydia, Klebsiella, and Staphylococcus aureus can also cause infections in neonates, they are not typically associated with GBS in the context of neonatal sepsis. Chlamydia is more related to conjunctivitis and respiratory infections. Klebsiella can cause infections but is less commonly associated with GBS, and Staphylococcus aureus, while an important pathogen, is not specifically linked with GBS in the context of neonatal sepsis