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A woman is 12 hours postpartum with a WBC count of 25,000. What does this indicate?

An expected range

A white blood cell (WBC) count of 25,000 postpartum, particularly at 12 hours after delivery, is often considered within an expected range. It is well-documented that leukocytosis, or an elevated WBC count, is a normal physiological response after the stress of labor and delivery. This increase is primarily due to the release of neutrophils and an elevation in white blood cell production, which can be a protective mechanism after childbirth.

During the postpartum period, the body is adjusting to the significant changes that occur during labor, and an elevated WBC count can reflect this adrenal response, which does not necessarily indicate infection or other pathological conditions within the first 24 hours post-delivery. In fact, levels can be as high as 25,000 to 30,000 in the immediate postpartum period without signifying an underlying problem.

The other potential interpretations of the WBC count in this scenario — such as dehydration or infection — would typically warrant further clinical signs or symptoms to justify further action like requiring antibiotics or surgical intervention. However, without additional symptoms such as fever, chills, or signs of localized infection, an elevated count alone shortly after delivery can be interpreted as an expected physiological response.

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Dehydration and a need to force fluids

Infection and a need for an antibiotic order

A condition requiring immediate surgical intervention

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